Pharmaceutical Danger

Reports of Xarelto Adverse Events

Posted by on Sep 29, 2014 in Pharmaceutical Danger | 0 comments

One of the latest anticoagulants in the market Xarelto (rivaroxaban) was approved by the Food and Drug Administration for US distribution in July 2011 by Janssen Ortho LLC (a division of Johnson& Johnson) under license with Bayer Corp. Xarelto is part of a class of anticoagulants called direct factor Xa (10-a) inhibitors (xabans) that are designed to reduce the incidence of abnormal blood clotting associated with patients with atrial fibrillation. Xaretol specifically is also designed for deep vein thrombosis and pulmonary embolism treatment as well as a prophylactic for patients who have recently undergone hip or knee replacement.

Xarelto has been proven to efficacious in these therapies. Unfortunately, it works too well. A growing number of patients have suffered from a potentially fatal side effect: uncontrollable bleeding. It is pointed out at the website of Williams Kherkher that this bleeding is potentially fatal when associated with Xarelto because there is no approved or effective reversal agent or process to halt the blood thinning effects of Xarelto. Some have attempted using dialysis to flush out Xarelto for the system but it is not considered a guaranteed remedy by medical experts. The best that patients who experience this side effect can do is to ride it out with some medical support. Xarelto stays in the system for as long as 12 hours, which can be a very long time for someone who is bleeding copiously.

According to the Institute for Safe Medication Practives (ISMP), blood thinners are the most frequently reported drugs for serious side effects to the FDA, and this includes Xarelto. For rivaroxaban, the most commonly reported adverse event is hemorrhage, gastrointestinal hemorrhage, hematoma, edema peripheral, deep vein thrombosis and pulmonary embolism. And the incidents are not confined to the US. In Germany, there were 968 adverse events with 72 deaths reported in 2013.

If you have been taking Xarelto and experienced serious uncontrollable bleeding, you don’t have to just be a statistic. You can sue for compensation for your medical and other costs and teach the responsible parties to take their duty of care to their clients more seriously. Consult with a Xarelto lawyer on how these can be carried out.

Read More